VEGFA, vascular endothelial growth factor A, 7422

N. diseases: 1899; N. variants: 59
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0004096
Disease: Asthma
Asthma
0.400 AlteredExpression disease BEFREE Relationship between neurokinin 2 receptor gene polymorphisms and serum vascular endothelial growth factor levels in patients with toluene diisocyanate-induced asthma. 16961715 2006
CUI: C0004096
Disease: Asthma
Asthma
0.400 AlteredExpression disease BEFREE The levels of HIF-1α and VEGF increased in lung tissue and bronchial fluid of patients with asthma and in the nasal fluid of patients with rhinitis after challenge. 21517900 2011
CUI: C0004096
Disease: Asthma
Asthma
0.400 AlteredExpression disease BEFREE It has been shown that treatment of asthma patients decreases VEGF levels, and inhibition of VEGF diminishes asthma symptoms in mice. 22519966 2012
CUI: C0004096
Disease: Asthma
Asthma
0.400 AlteredExpression disease BEFREE In addition, there were no correlations between VEGF levels and asthma control test scores. 26996348 2017
CUI: C0004096
Disease: Asthma
Asthma
0.400 AlteredExpression disease BEFREE EBT is increasing in severe asthma and is significantly modulated by VEGF levels. 29176061 2018
CUI: C0004096
Disease: Asthma
Asthma
0.400 AlteredExpression disease BEFREE Allergen treatment and lung-specific vascular endothelial growth factor (VEGF) expression induced asthma-like pathologies in the murine lungs. 21595947 2011
CUI: C0004096
Disease: Asthma
Asthma
0.400 AlteredExpression disease BEFREE VEGF levels were measured in respiratory secretions from patients with asthma, before and during rhinovirus-induced exacerbations. 16461129 2006
CUI: C0004096
Disease: Asthma
Asthma
0.400 AlteredExpression disease LHGDN Vascular endothelial growth factor overexpression in induced sputum of children with bronchial asthma. 18298425 2009
CUI: C0004096
Disease: Asthma
Asthma
0.400 AlteredExpression disease LHGDN Administration of VEGF receptor inhibitors reduced the pathophysiologic signs of asthma and decreased the increased expression of MMP-9 after ovalbumin inhalation. 16645174 2006
CUI: C0004096
Disease: Asthma
Asthma
0.400 AlteredExpression disease BEFREE PDGFBB and VEGF levels were significantly associated with asthma. 31586492 2019
CUI: C0004096
Disease: Asthma
Asthma
0.400 Biomarker disease BEFREE Vascular endothelial growth factor (VEGF) has been implicated in inflammatory and airway blood vessel remodeling in asthmatics. 31831011 2019
CUI: C0004096
Disease: Asthma
Asthma
0.400 Biomarker disease BEFREE C. pneumoniae infection of BECs may play a role in the pathogenesis of asthma through the enhanced production of CCL20 and VEGF. 19479364 2009
CUI: C0004096
Disease: Asthma
Asthma
0.400 Biomarker disease CTD_human Acute and chronic changes of vascular endothelial growth factor (VEGF) in induced sputum of toluene diisocyanate (TDI)-induced asthma patients. 15201500 2004
CUI: C0004096
Disease: Asthma
Asthma
0.400 Biomarker disease CTD_human Manganese (II) induces chemical hypoxia by inhibiting HIF-prolyl hydroxylase: implication in manganese-induced pulmonary inflammation. 19263519 2009
CUI: C0004096
Disease: Asthma
Asthma
0.400 Biomarker disease LHGDN The aim of this study was to compare vascular endothelial growth factor (VEGF) and its receptor foetal liver kinase (Flk)-1 expression between seasonal AR patients with or without asthma and non-allergic controls as well as that between AR patients with and without asthma. 17651148 2007
CUI: C0004096
Disease: Asthma
Asthma
0.400 Biomarker disease LHGDN Immunomodulatory role of vascular endothelial growth factor and angiopoietin-1 in airway remodeling. 17168735 2006
CUI: C0004096
Disease: Asthma
Asthma
0.400 Biomarker disease BEFREE Fatty acid binding protein 4 regulates VEGF-induced airway angiogenesis and inflammation in a transgenic mouse model: implications for asthma. 23391391 2013
CUI: C0004096
Disease: Asthma
Asthma
0.400 Biomarker disease LHGDN Vascular endothelial growth factor-mediated induction of angiogenesis by human rhinoviruses. 16461129 2006
CUI: C0004096
Disease: Asthma
Asthma
0.400 Biomarker disease BEFREE The cytokine and potent angiogenic factor vascular endothelial growth factor (VEGF) plays an important role in airway remodelling in various airway diseases such as idiopathic pulmonary fibrosis, pulmonary hypertension, lung cancer, asthma and chronic obstructive pulmonary disease (COPD). 17906365 2007
CUI: C0004096
Disease: Asthma
Asthma
0.400 Biomarker disease BEFREE Role of licochalcone A in VEGF-induced proliferation of human airway smooth muscle cells: implications for asthma. 28635361 2017
CUI: C0004096
Disease: Asthma
Asthma
0.400 Biomarker disease BEFREE Experimental models and expression studies suggest that anti-vascular endothelial growth factor (VEGF) receptor strategies may be of use in patients with emphysema, whereas anti-HER1-directed strategies may be more useful in patients with pulmonary mucus hypersecretion, as seen in chronic bronchitis and asthma. 17406066 2007
CUI: C0004096
Disease: Asthma
Asthma
0.400 Biomarker disease BEFREE Vascular endothelial growth factor (VEGF) has been implicated in inflammatory and airway blood vessel remodeling in asthma. 28056993 2017
CUI: C0004096
Disease: Asthma
Asthma
0.400 Biomarker disease BEFREE VEGFA was a hub protein in both the PPI networks of DEGs in notSA vs. NC and SA vs. NC. 27842724 2017
CUI: C0004096
Disease: Asthma
Asthma
0.400 Biomarker disease BEFREE Nasal VEGF was also measured in a cohort of asthmatics with verified rhinovirus and respiratory syncytial virus (RSV) infection. 16555282 2006
CUI: C0004096
Disease: Asthma
Asthma
0.400 Biomarker disease BEFREE We conclude that ASM-derived VEGF, through modulation of the extracellular matrix, may play an important role in airway remodeling seen in asthma. 14633511 2004